Treatment of face and scalp solar (actinic) keratosis with daylight-mediated photodynamic therapy is possible throughout the year in Australia: Evidence from a clinical and meteorological study.
Identifieur interne : 001502 ( Main/Exploration ); précédent : 001501; suivant : 001503Treatment of face and scalp solar (actinic) keratosis with daylight-mediated photodynamic therapy is possible throughout the year in Australia: Evidence from a clinical and meteorological study.
Auteurs : Lynda Spelman [Australie] ; Diana Rubel [Australie] ; Dedee F. Murrell [Australie] ; Jo-Ann See [Australie] ; Daniel Hewitt [Australie] ; Peter Foley [Australie] ; Robert Salmon [Australie] ; Delphine Kerob [France] ; Thierry Pascual [France] ; Stephen Shumack [Australie] ; Pablo Fernandez-Penas [Australie]Source :
- The Australasian journal of dermatology [ 1440-0960 ] ; 2016.
Descripteurs français
- KwdFr :
- Acide amino-lévulinique (usage thérapeutique), Australie, Dermatoses du cuir chevelu (traitement médicamenteux), Dermatoses faciales (traitement médicamenteux), Facteurs temps, Humains, Kératose actinique (traitement médicamenteux), Lumière du soleil, Météorologie (), Photosensibilisants (usage thérapeutique), Photothérapie dynamique.
- MESH :
- traitement médicamenteux : Dermatoses du cuir chevelu, Dermatoses faciales, Kératose actinique.
- usage thérapeutique : Acide amino-lévulinique, Photosensibilisants.
- Australie, Facteurs temps, Humains, Lumière du soleil, Météorologie, Photothérapie dynamique.
English descriptors
- KwdEn :
- MESH :
- chemical , therapeutic use : Aminolevulinic Acid, Photosensitizing Agents.
- drug therapy : Facial Dermatoses, Keratosis, Actinic, Scalp Dermatoses.
- statistics & numerical data : Meteorology.
- Australia, Humans, Photochemotherapy, Sunlight, Time Factors.
Abstract
Solar (actinic) keratosis (AK) is an emergent concern worldwide and is associated with an increased risk of development of non-melanoma skin cancer, especially squamous cell carcinoma. Daylight-mediated photodynamic therapy (DL-PDT) using methyl aminolaevulinate cream has proved to be an effective, nearly painless, and more convenient alternative to conventional PDT for the treatment of AK. In a phase III, randomised, controlled trial performed in Australia, the mean irradiance (light intensity) received by patients during DL-PDT treatment, assessed via a spectroradiometer, was 305 W/m(2) (min. 40 to max. 585 W/m(2) ) with similar efficacy irrespective of intensity or dose. The objective of the present meteorological study was to assess the suitability of natural daylight to perform DL-PDT for the treatment of face and scalp AK during different periods of the year and different geographical locations and latitudes across Australia.
DOI: 10.1111/ajd.12295
PubMed: 25827200
Affiliations:
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data)</term><term>Photochemotherapy</term><term>Photosensitizing Agents (therapeutic use)</term><term>Scalp Dermatoses (drug therapy)</term><term>Sunlight</term><term>Time Factors</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Acide amino-lévulinique (usage thérapeutique)</term><term>Australie</term><term>Dermatoses du cuir chevelu (traitement médicamenteux)</term><term>Dermatoses faciales (traitement médicamenteux)</term><term>Facteurs temps</term><term>Humains</term><term>Kératose actinique (traitement médicamenteux)</term><term>Lumière du soleil</term><term>Météorologie ()</term><term>Photosensibilisants (usage thérapeutique)</term><term>Photothérapie dynamique</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Aminolevulinic Acid</term><term>Photosensitizing Agents</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Facial Dermatoses</term><term>Keratosis, Actinic</term><term>Scalp Dermatoses</term></keywords><keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>Meteorology</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Dermatoses du cuir chevelu</term><term>Dermatoses faciales</term><term>Kératose actinique</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Acide amino-lévulinique</term><term>Photosensibilisants</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Australia</term><term>Humans</term><term>Photochemotherapy</term><term>Sunlight</term><term>Time Factors</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Australie</term><term>Facteurs temps</term><term>Humains</term><term>Lumière du soleil</term><term>Météorologie</term><term>Photothérapie dynamique</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Solar (actinic) keratosis (AK) is an emergent concern worldwide and is associated with an increased risk of development of non-melanoma skin cancer, especially squamous cell carcinoma. Daylight-mediated photodynamic therapy (DL-PDT) using methyl aminolaevulinate cream has proved to be an effective, nearly painless, and more convenient alternative to conventional PDT for the treatment of AK. In a phase III, randomised, controlled trial performed in Australia, the mean irradiance (light intensity) received by patients during DL-PDT treatment, assessed via a spectroradiometer, was 305 W/m(2) (min. 40 to max. 585 W/m(2) ) with similar efficacy irrespective of intensity or dose. The objective of the present meteorological study was to assess the suitability of natural daylight to perform DL-PDT for the treatment of face and scalp AK during different periods of the year and different geographical locations and latitudes across Australia.</div></front></TEI><affiliations><list><country><li>Australie</li><li>France</li></country><region><li>Nouvelle-Galles du Sud</li><li>Île-de-France</li></region><settlement><li>Paris</li><li>Sydney</li></settlement><orgName><li>Université de Sydney</li></orgName></list><tree><country name="Australie"><noRegion><name sortKey="Spelman, Lynda" sort="Spelman, Lynda" uniqKey="Spelman L" first="Lynda" last="Spelman">Lynda Spelman</name></noRegion><name sortKey="Fernandez Penas, Pablo" sort="Fernandez Penas, Pablo" uniqKey="Fernandez Penas P" first="Pablo" last="Fernandez-Penas">Pablo Fernandez-Penas</name><name sortKey="Foley, Peter" sort="Foley, Peter" uniqKey="Foley P" first="Peter" last="Foley">Peter Foley</name><name sortKey="Hewitt, Daniel" sort="Hewitt, Daniel" uniqKey="Hewitt D" first="Daniel" last="Hewitt">Daniel Hewitt</name><name sortKey="Murrell, Dedee F" sort="Murrell, Dedee F" uniqKey="Murrell D" first="Dedee F" last="Murrell">Dedee F. Murrell</name><name sortKey="Rubel, Diana" sort="Rubel, Diana" uniqKey="Rubel D" first="Diana" last="Rubel">Diana Rubel</name><name sortKey="Salmon, Robert" sort="Salmon, Robert" uniqKey="Salmon R" first="Robert" last="Salmon">Robert Salmon</name><name sortKey="See, Jo Ann" sort="See, Jo Ann" uniqKey="See J" first="Jo-Ann" last="See">Jo-Ann See</name><name sortKey="Shumack, Stephen" sort="Shumack, Stephen" uniqKey="Shumack S" first="Stephen" last="Shumack">Stephen Shumack</name></country><country name="France"><region name="Île-de-France"><name sortKey="Kerob, Delphine" sort="Kerob, Delphine" uniqKey="Kerob D" first="Delphine" last="Kerob">Delphine Kerob</name></region><name sortKey="Pascual, Thierry" sort="Pascual, Thierry" uniqKey="Pascual T" first="Thierry" last="Pascual">Thierry Pascual</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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